# R Code for "Combined expression of FOXO and Tribbles proteins predicts survival of glioma patients"

This repository contains the R code developed for the analyses presented in the paper **"Combined expression of FOXO and Tribbles proteins predicts survival of glioma patients"**. The code facilitates data import, cleaning, and editing, as well as statistical analyses, including survival analysis and expression level comparisons. These analyses were performed across multiple independent datasets.

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## Overview

The scripts in this repository were developed to support the analyses described in the paper **"[Paper Title]"**. The main objectives of the analysis include:

1. Importing and cleaning raw data from multiple independent glioma datasets.

2. Performing survival analysis to evaluate patient outcomes.

3. Comparing gene expression levels across groups using ANOVA.

4. Generating reproducible results for multiple datasets.

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## Repository Structure

The repository includes files for the following 4 datasets:

1. TCGA

2. CGGA

3. REMBRANDT

4. Gravendeel

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## Dependencies

The analysis requires R and the following R packages:

- `TCGAbiolinks`:

- `SummarizedExperiment`:

- `tidyverse`:

- `magrittr`:

- `survival`:

- `dplyr`:

- `survminer`:

- `gridExtra`:

- `GEOquery`:

- `Biobase`: