- CASE STUDY: Studying the expression profile of 156 lung tumors and adjacent normal lung tissue samples
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Identify pathways which genes are differentially expressed in various groups of samples
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Compare the expression profile of samples using correlations
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Run Oncodrive to identify the genes that are significantly up-regulated taking into account a set of tumour samples
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Compare and combine the significantly up-regulated genes in our experiment and other lung experiments imported from IntOGen
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Compare the overlap of significantly up-regulated genes in our experiment and in other lung experiments imported from IntOGen
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Analyse the conservation patterns of genes involved in different biological processes
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Identify the transcription factors involved in the regulation of expression in different tissues
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Compare the expression pattern of genes expressed in different tissues
The videos we have put online for this case study we are accessible on Youtube.
Watch the whole case study as a YouTube playlist
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Get prepared to start working
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See which genes are altered in a mutually exclusive manner
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See which genes are significantly influenced by genomic alterations in their locus
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Asses transcription level for pathways for each sample in the study
