A Claude Code plugin that gives Claude the ability to run phi CLI commands for the dyno protein analysis platform.

Installs the /dyno-phi:phi skill, which lets Claude:

• Run the full scoring workflow (research → fetch → upload → filter → download)
• Submit jobs to ESMFold, AlphaFold2, and ProteinMPNN
• Score and filter candidates using pLDDT, pTM, ipTM, iPAE, and RMSD
• Manage datasets and jobs

Install the CLI and set your API key:

pip install dyno-phi
export DYNO_API_KEY=ak_...
phi login   # verify connectivity

Load the plugin directly with --plugin-dir:

claude --plugin-dir ./phi-plugin

Then use the skill in Claude Code:

/dyno-phi:phi upload ./designs/
/dyno-phi:phi filter --preset default --wait
/dyno-phi:phi scores

Or just describe what you want — Claude will invoke the skill automatically:

Upload the PDB files in ./designs/ and run the default filter pipeline.

Part of the phi-cli repository.