A new manuscript titled “African pygmy mouse iPSCs as a model for in vitro embryogenesis, interspecies chimerism, and blastocyst complementation” has been published in Cell Reports Methods. This work expands the repertoire of mammalian iPSC models and establishes the African pygmy mouse as a powerful system for investigating pluripotency, interspecies chimerism, and regenerative strategies. Congratulation to all authors!
Very happy to share that Greta's main PhD project, a close joint collaboration between the Snedeker and De Bock labs, has now been published in Science Translational Medicine.
A warm welcome to our new lab members Sandy Hossmann as a Transgenic Specialist, Natasa Savic as Genome Engineering Expert, and Arion Förtsch as our new Bioinformatician. We wish you all a very successful start!
Guillermo`s main PhD publication was published in Nature Cardiovascular Research! He used single-cell RNA sequencing and spatial transcriptomics to analyze the composition of the muscle microenvironment in non-ischemic patients and patients with peripheral artery disease and identified ATF3/ATF4+endothelial cells that exhibit altered angiogenic and immune regulatory profiles during PAD and confirmed that ATF4 signaling in ECs is required for effective ischemia recovery.
A new manuscript detailing enhanced culture conditions for derivation of bovine muscle cells has been published in Advanced Science. This study represents the first paper on cultivated meat from our lab, and has been featured extensively in media outlets. Congratulations to Christine, Adhi and coauthors on this wonderful achievement!