CAMBRIDGE, Mass.--(BUSINESS WIRE)--Crossbow announced it raised $77 million in a Series B financing that will advance the development of TCR-mimetic antibody therapies to treat cancer ... .
Crossbow is developing a broad portfolio of novel T-cell engager (TCE) therapies that potently target peptide human leukocyte antigen (pHLA) on cancer cells, using antibodies that mimic T-cell receptors (TCR-mimetics).
Preclinical assessment of MAGE-A4 specific TCR-NK cells against solid tumors ... Zelluna is pioneering allogeneic off-the-shelf T Cell Receptor-based NaturalKiller (TCR-NK) cell therapies for the treatment of solid cancers.
"ZI-MA4-1 will be the first MAGE-A4-targeting TCR-NK cell therapy to enter clinical testing globally and represents the culmination of rigorous scientific, non-clinical, CMC and regulatory work.
) Zelluna announces collaboration with Etcembly for AI-enabled TCR engineering ... The engineered receptors will be fully owned by Zelluna and developed for use within Zelluna's proprietary TCR-NK platform ... About Zelluna's TCR-NK Platform. ... TCR-NK.
Fapon's Human/Cyno Cross-Reactive CD3/TCRVHH... The cornerstone of our technology is a series of cross-species CD3/TCR VHHs with different affinity binding to both human and cynomolgus monkeys.