JMIR Research Protocols

In mixed methods research (MMR), researchers combine elements of qualitative and quantitative methodologies, methods of data collection and analysis, viewpoints, and integration procedures to gain a deeper understanding of what is being studied, design culturally specific tools, and explore the conditions under which health care interventions succeed or fail. Integration is considered the hallmark of MMR and can occur at various levels, such as sampling, data collection, and analysis. MMR is particularly useful for investigating complex, multilevel programs and interventions and is well-suited to address research problems involving knowledge translation, program evaluations, or comparisons of therapeutic interventions. Although there are many potential benefits of mixed methods in health research, the extent to which mixed methods studies implement integration remains limited, with this specific gap persisting for almost 20 years. The Good Reporting of a Mixed Methods Study (GRAMMS) reporting guidelines were developed in 2008 to help improve the quality of reporting in mixed methods reports and articles. Since then, the field of mixed methods has evolved rapidly, and the guideline no longer reflects current practices and innovations.

Total hip arthroplasty is a highly successful procedure for treating hip arthritis, improving patients’ pain, function, and quality of life (QoL). Scarce publications on total hip arthroplasty performance using Brazilian-manufactured materials report results comparable to those from other countries.

After a burn injury, the survivors have to manage and integrate the physical, psychological, and social consequences of their injury into their daily lives, such as functional limitations, aesthetic complaints, and fatigue. How successful survivors of burn injuries are at this depends on their self-management skills. Health care professionals play an important role in supporting the self-management of survivors of burn injuries. Currently, there are no burn-specific self-management support interventions. Therefore, we developed a self-management support intervention for survivors of burn injuries, called BreeZe (Brandwonden en Zelfmanagement).

Health inequities represent a persistent and multifaceted challenge, particularly pronounced for individuals with intellectual and developmental disabilities (IDDs), including Down syndrome (DS). This population frequently faces systemic barriers to care and is at higher risk of adverse health outcomes Despite advances, gaps persist in health care professionals’ training for caring for this population. Undergraduate medical education constitutes a crucial component in addressing these disparities and promoting inclusive care, especially through practical experiences for future physicians.

In Ayurveda, (diabetes mellitus) is considered (one among eight diseases difficult to treat and cure). (three bio-humor in Ayurveda) with certain metabolic factors are involved in its pathogenesis. Frequent urination is a common symptom of this disease. Diabetes mellitus can be confused with type 2 diabetes mellitus in conventional science due to the resemblance in cardinal features.

Noninferiority (NI) trial designs that investigate whether an experimental intervention is no worse than the standard of care have been used increasingly in recent years. The robustness of the conclusions depends in part on the analysis population set used. In NI settings, the intention-to-treat (ITT) and per-protocol (PP) analysis sets are most common. The ITT analysis has been considered anticonservative compared with the PP analysis.

Cardiovascular disease (CVD) is the leading cause of death worldwide. Individuals with lower income or experiencing financial hardship face a significantly higher risk of developing CVD. However, there is a lack of in-depth insight into their experiences with CVD, and specific attention to women is essential.

Undergraduate nursing students are expected to perform a high-stakes clinical skills test, which ultimately determines their ability to engage in clinical practice. With intake number of students growing nationally, clinical instructors are modifying these skills tests to be shorter in duration as an attempt to meet scheduled class times, severely decreasing the assessments’ accuracy and increasing student stress.

Structural ableism, defined as the processes, policies, and institutions that privilege able-bodied people over disabled people, is a root cause of health inequalities faced by the disability community. Unlike other forms of structural oppression, there are currently no adequate measurements for structural ableism and its impacts. Therefore, a necessary first step to addressing health inequities that impact the disability community is to create validated measures of structural ableism.

Nonspecific low back pain (NSLBP) is a significant global public health concern that affects the health and well-being of individuals across different age groups, limiting their daily activities and reducing their quality of life. As Tuina (Chinese therapeutic massage) therapy and medicated oil are widely used in China, it is necessary to design a randomized clinical trial to assess the effectiveness of Tuina combined medicated oil (TNO) in treating NSLBP.

Traditional Chinese medicine (TCM) functions according to the concepts of “holism” and treatment based on syndrome differentiation, and it has achieved good clinical results in treating patients with dysmenorrhea, which is a common gynecological disorder. However, there are currently no international clinical practice guidelines involving TCM therapies for dysmenorrhea. This study aims to establish a protocol for the development of such guidelines.

Caregivers to a person diagnosed with a glioblastoma often face significant responsibilities, balancing the demands of care with the complexities of the disease and treatment trajectory, while also coping with concerns and uncertainty of the future. Caregivers report unmet needs of information and support throughout the patient’s disease and treatment trajectory, and they may benefit from targeted supportive care interventions.