AGCoL SyMAP - Synteny Mapping and Analysis Program UA
BIO5
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SyMAP (Synteny Mapping and Analysis Program) is a software package for detecting, displaying, and querying syntenic relationships between sequenced genomes.
  • It is designed for divergent eukaryotic genomes (not bacteria).
  • For gene synteny and fast computation, have SyMAP mask the non-genic sequence.
    For new gene discovery but slower computation, leave the sequence un-masked.
  • It can align a draft genome to a fully sequenced genome and order the draft (see Peach).
  • The query and display is designed for the comparison of a few genomes at a time (i.e. 2-4).

Latest SyMAP release: v5.8.1 (11-March-2026), see Release Notes.

Download
  symap_5.tar.gz
  - Executable and demo files
 
Documentation
  Index of Docs
  System Guide - Build synteny
  User Guide - View synteny
  SyMAP Tour
 
Also see
  TCW: Comparative transcriptomes
Click an image to see the closeup.
symapPlants 2d-3chr
dotplot-3g circle-two-genome
This project was partially supported by the National Research Initiative of USDA's National Institute of Food and Agriculture, grant #0214643.
All upgrades since release 7-Nov-2016 have been developed by Cari Soderlund without funding.
SyMAP was originally written for diverse plant genomes with short introns, but has been modified to work for the long introns of mammalian genomes, and less diverse genomes.

Publications

C. Soderlund, M. Bomhoff, and W. Nelson (2011) SyMAP v3.4: a turnkey synteny system with application to plant genomes Nucleic Acids Research 39(10):e68 Link

C. Soderlund, W. Nelson, A. Shoemaker and A. Paterson (2006) SyMAP: A system for discovering and viewing syntenic regions of FPC maps. Genome Research 16:1159-1168. Link

Email: [email protected]