Riprap Predict RNA structural disruptions induced by single nucleotide variants

We introduce a novel computational framework–RIboSNitch Predictor based on Robust Analysis of Pairing probabilities (Riprap). Riprap identifies structurally disrupted regions induced by any given SNVs based on robust analysis of local structural configurations between wild-type and mutant RNA sequences.

1. Prerequisites
2. Run Riprap

1. Source code
2. Sample data

1. Sample input
2. Command example
3. Sample output

Lin, J., Zhang, Y., Chen, Y., & Ouyang, Z. (2020). Identification and analysis of RNA structural disruptions induced by single nucleotide variants using Riprap and RiboSNitchDB

Use of Riprap is free for academic users under the GNU General Public License (GPL). Commercial users please contact the authors.

Zhengqing Ouyang: [email protected] Jianan Lin: [email protected]