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taliaora/README.md

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LinkedIn GitHub Website

Hi! I'm Natalia Sikora, I'm a PhD Candidate (defended, working on corrections) and a postdoctoral fellow specialising in bioinformatics, AI in medical applications, xAI, and multimodal data integration. As a hobby, I enjoy playing with finance data (hello there, fellow investors!), data analytics, and visualisations.

πŸ¦‰πŸ“š Recent Publications

🌸 Perturbing LSD1 and WNT rewires transcription to synergistically induce AML differentiation
Hosseini, A., Dhall, A., Ikonen, N., Sikora, N. et al. Nature, 2025
β†’ Demonstrates how combinatorial targeting of LSD1 and WNT signaling drives transcriptional reprogramming and differentiation in AML.

🌸 ColonScopeX: Leveraging Explainable Expert Systems with Multimodal Data for Improved Early Diagnosis of Colorectal Cancer
Sikora, N., Manschke, R.L., Tang, A.M., Dunstan, P., Harris, D.A., Yang, S. AAAI-25 B1
β†’ Introduces an explainable multimodal AI framework integrating blood biomarkers and patient metadata to aid early colorectal cancer and polyp detection.

🌸 Measuring Fairness in Financial Transaction Machine Learning Models
Ayvaz, D.S., Belenguer, L., He, H., Kanubala, D.D., Li, M., Low, S., Mougan, C., Onwuegbuche, F.C., Pi, Y., Sikora, N., Tran, D., Verma, S., Wang, H., Xie, S., Pelletier, A. arXiv preprint, 2025
β†’ A Mastercard and Alan Turing Institute collaboration tackling fairness evaluation in financial ML models through explainable and responsible AI practices.

GitHub Streak

Profile Views

AI & Machine Learning

PyTorch TensorFlow Keras HuggingFace Transformers Explainable AI AI Ethics

🧬 Bioinformatics Data Science, Omics Techniques

Seurat scanpy Bioconductor Multi-omics Metabolomics Nextflow nf-core sc-Joint GLUE Harmony scRNA-seq scATAC-seq ChIP-seq ATAC-seq CUT&RUN FACS CNV Differential Expression

Data Integration & Modeling

Multi-omics Metabolomics

πŸ“Š Data Visualization

ggplot2 matplotlib Plotly

πŸ‘¨β€πŸ’» Programming Languages & Frameworks

Python R Java SQL Django Flask HTML5

🧰 Tools, Workflow, Development Practices

Docker Git GitLab Nextflow nf-core Linux Slurm Agile OOP DevOps

Pinned Loading

  1. sc_GNN sc_GNN Public

    Python

  2. MarcAmil30/Talk2Me_Hackathon_2025 MarcAmil30/Talk2Me_Hackathon_2025 Public

    Bio X Ai Hackathon

    HTML