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TOMBOMBADIL

Tree-free Omega Mapping By Observing Mutations of Bases and Amino acids Distributed Inside Loci

"Old Tom Bombadil is a merry fellow! Bright Blue his jacket is, and his boots are yellow!" —Tom Bombadil

TOMBOMBADIL - method for estimating dN/dS directly from alignments

Original implementation in Stan https://github.com/bacpop/TOMBOMBADIL

Work is based on Genomegamap https://doi.org/10.1093/molbev/msaa069

Fitting dN/dS model to data

run using
poetry install
poetry run python tombombadil-runner.py --alignment porB3.carriage.noindels.txt

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JAX prototype of TOMBOMBADIL

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